Tuesday, April 30, 2013

Jerry Lewis makes appearance at 'King of Comedy'

NEW YORK (AP) ? The Tribeca Film Festival has ended on a royal note with Jerry Lewis showing up at the 30th anniversary screening of "The King of Comedy."

The 87-year-old comedian-actor walked out to thunderous applause after the screening Saturday, joining co-star Robert De Niro and director Martin Scorsese.

Lewis answered questions about the making of the film and brought the audience to laughter with a tale about a guy he met on a subway train.

In the movie, Lewis plays a talk-show host kidnapped by a deranged comedian played by De Niro.

De Niro founded the festival with producers Jane Rosenthal and Craig Hatkoff as a way to rebuild the neighborhood where the World Trade Center fell in the 9/11 attacks.

___

Follow John Carucci on Twitter at www.twitter.com/jacarucci

Source: http://news.yahoo.com/jerry-lewis-makes-appearance-king-comedy-061812928.html

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Rare, lethal childhood disease tracked to protein

Apr. 29, 2013 ? A team of international researchers led by Northwestern Medicine scientists has identified how a defective protein plays a central role in a rare, lethal childhood disease known as Giant Axonal Neuropathy, or GAN. The finding is reported in the May 2013 Journal of Clinical Investigation.

GAN is an extremely rare and untreatable genetic disorder that strikes the central and peripheral nervous systems of young children. Those affected show no symptoms at birth; typically around age three the first signs of muscle weakness appear and progress slowly but steadily. Children with GAN experience increasing difficulty walking and are often wheelchair-bound by age 10. Over time, they become dependent on feeding and breathing tubes. Only a few will survive into young adulthood.

In GAN patients, nerve cells are swollen with massive build-ups of structures called intermediate filaments, cytoskeletal components that give cells their shape and mechanical properties. Goldman's team found that gigaxonin, a protein encoded by the gene involved in GAN, regulates normal turnover of the protein building blocks that form a cell's intermediate filaments. Mutations in this gene result in the malfunctioning of gigaxonin, which leads to the abnormal build-up of intermediate filaments and eventually disrupts the normal functioning of nerve cells.

"This important new research pinpoints the mechanism that allows intermediate filaments to rapidly build up in GAN patients," says Robert Goldman, chair of the department of cell and molecular biology at Northwestern University Feinberg School of Medicine. Goldman has studied the structural proteins of cells for more than 30 years.

"This is a huge step forward for GAN research," said Lori Sames, co-founder and CEO of Hannah's Hope Fund, the leading GAN disease organization. "GAN is juvenile ALS, but even worse. Not only do motor neurons die out, so do the sensory neurons. To find a medicinal therapy, you really need to know what mechanism to target. And thanks to Dr. Goldman's work, now we do."

To identify gigaxonin's role, scientists used cells known as fibroblasts obtained from skin biopsies of children with GAN. The cells were then grown in lab cultures, and they also contained large abnormal aggregates of intermediate filaments. When scientists introduced healthy gigaxonin genes into both control and patient fibroblasts, the results were dramatic. The abnormal aggregates of intermediate filaments disappeared. However, the cytoskeleton's two other major systems, microtubules and actin filaments were not affected by this treatment.

The study's lead author, Northwestern University postdoctoral fellow Saleemulla Mahammad, stressed that this discovery may also have implications for more common types of neurodegenerative diseases that are also characterized by large accumulations of intermediate filament proteins, including Alzheimer's disease and Parkinson's disease.

"Our results suggest new pathways for disease intervention," he said. "Finding a chemical component that can clear the intermediate filament aggregations and restore the normal distribution of intermediate filaments in cells could one day lead to a therapeutic agent for many neurological disorders."

Mahammad and other members of the Goldman Laboratory collaborated with Puneet Opal, M.D., associate professor in the Ken and Ruth Davee department of neurology and cell and molecular biology, along with researchers in the laboratory of Pascale Bomont, at the INSERM neurological institute in Montpelier, France, and the laboratory of Jean-Pierre Julien at the Universit? Laval in Quebec, Canada.

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The above story is reprinted from materials provided by Northwestern University, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Saleemulla Mahammad, S.N. Prasanna Murthy, Alessandro Didonna, Boris Grin, Eitan Israeli, Rodolphe Perrot, Pascale Bomont, Jean-Pierre Julien, Edward Kuczmarski, Puneet Opal, Robert D. Goldman. Giant axonal neuropathy?associated gigaxonin mutations impair intermediate filament protein degradation. Journal of Clinical Investigation, 2013; DOI: 10.1172/JCI66387

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/5IQlUZchprQ/130429164909.htm

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Google Now for iOS hands-on

Google Now for iOS handson

Google Now is, perhaps, one of the more compelling reasons to opt for an Android device over iOS. But, Mountain View is smart enough to realize that its big push to deliver information pre-emptively would be severely hampered if it was isolated to one platform. So, here we are, almost a year after Now debuted with the launch of Jelly Bean, and the (mis)labeled Siri competitor has finally landed on Apple's mobile OS. Obviously, to truly come to grips with a product like this, you'd need days or weeks to truly judge it, but we're familiar enough with the Android version to feel comfortable passing along our initial impressions. So head on after the break to see whether or not Google was able to replicate its virtual assistant magic on iOS.

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Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/2MsIyT7febc/

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Sharapova beats Li Na to win Porsche GP again

STUTTGART, Germany (AP) ? Maria Sharapova beat Li Na 6-4, 6-3 on Sunday to successfully defend her WTA Porsche Grand Prix title in a final between the last two French Open champions.

The top-seeded Russian swept to her second title of the year after winning in Indian Wells, Calif. She became the first player to retain the Stuttgart title since Lindsey Davenport in 2005.

"I thought it'd be the toughest match of the tournament, but I played my best tennis today," Sharapova said. "I was able to step it up."

This was her 29th career title and 16th consecutive win on clay, dating to Rome last year. Since Stuttgart last year, she is 23-1 on clay. Her only loss was to Serena Williams in Madrid.

Sharapova, ranked No. 2, was using the Stuttgart tournament for her clay-court debut this season, as she did last year when she went on to capture the French Open.

The second-seeded Li had a double-fault on match point, with another one earlier in the final game.

"I was under pressure on her return," Li said. "She was aggressive."

Sharapova had to fight through three long three-setters to get to the championship match, but there was little drama in the final.

The Russian opened with a break and went up 4-1 before Li could pull back one break. But that was not enough, and Sharapova closed the set with a service winner.

"I tried to put it together from the start," Sharapova said.

Li, who became the first Chinese player to win a Grand Slam title with her victory at Roland Garros in 2011, simply didn't have enough consistency to threaten. Sharapova gained the key break in the seventh game of the second when Li sent a volley wide.

Sharapova holds a 9-5 career edge over Li, who beat her in the semifinals of the Australian Open, the year's first Grand Slam.

"I'm a little sad to lose," Li said. "But it's a pretty good start to my clay-court season."

Source: http://news.yahoo.com/sharapova-beats-li-na-win-porsche-gp-again-144816595.html

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Monday, April 29, 2013

Internet Marketing Tips And Advice For Businesses | Starting-Business

Internet Marketing Tips

Internet Marketing Tips

Admittedly, most people use Internet marketing to make money. In addition to the freedom owning a business provides, you must be passionate and dedicated to effective internet marketing skills. Put some of these tips into action and watch it happen!

Use tech tools to find how well your internet marketing campaign is working for you. There are a number of web companies that supply trackers to gauge the effectiveness of your marketing efforts. They measure things like visitors to your site, repeat visitors and how these visits translate into actual sales.

Finding information on effective marketing strategies does not have to cost a fortune. Many free resources are readily available. You could also join online communities, read blogs, go to seminars, or read eBooks.

Internet marketing is not an endeavor that is formulaic; in fact, it can be said that it is equal parts art and science. True, you need to understand the technical aspects of marketing, but you also have to feel your way through the realistic side of things. Be analytical of relevant data while expressing your creative side through the aesthetics and theme of your site.

Your site may be marketed as some kind of social marketing or club instead of your business. This will keep customers coming back, rather than visiting once and leaving immediately. This will also keep people interested in your site. You can also get some free advertising out of it. Give out different graphics and badges that people can use to advertise your site.

Do you have a product that no one else offers? This can drive a great deal of traffic towards your site as people search for this unique niche. The users will then likely look at your other products, bringing legitimacy to your site and therefore improving your page rank.

Find other businesses that would be interested in your products, and offer them promotional discounts of product or service bundles. This strategy expands your market and benefits both you and your product partners. Online travel agencies frequently do this, offering packages that cover hotel reservations, plane tickets and car rentals in bundled packages. This type of bundled package is great for companies that have products that can easily be linked with other complementary items that enhance their main product line.

To have proper internet marketing, you will want to be listed in Google. You need to know what terms people are searching for on Google that relate to your business. Google has a wide range of directories and listing options. Use them to your advantage.

Do you want to market online? If you want to increase the opt-in list of your website, provide your visitors with an incentive to give you their email information. Try offering freebies or maybe having a contest that they need to use their e-mail to participate in. It is much easier to get people?s email addresses if you offer them a chance at a tempting prize.

The information provided here to you shows that Internet marketing can be a profitable tool when used correctly. You ensure that all your effort is worth it, and you also get to pursue your passion.

Source: http://www.starting-business-uk.com/internet-marketing-tips-and-advice-for-businesses/

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PST: MLS to announce plans for 20th team in NYC

Major League Soccer has announced that in four to six weeks it will unveil plans for a new stadium in New York City to house the league?s 20th team.

Commissioner Don Garber discussed the plans while talking with reporters at halftime of Wednesday night?s contest between Toronto and Montreal?at BMO Field. In the conversation?Garber informed the public: ?We?are deeply engaged with potential ownership groups and we?re hopeful to be able to announce a 20th team within the next [four to six weeks].? The winning ownership group is expected to pay an expansion fee of?$100 million.

Garber had previously indicated that the league hoped?for something definitive on an expansion franchise in Queens by the end of 2013. He reiterated that desire on Wednesday, noting MLS? progress in getting a deal done.??We?re making progress,? Garber said of talks with New York City. ?We continue ? you?ve heard this for the last year ? but we continue to negotiate with the City of New York and meet with local political folks and community leaders to get support for the stadium we hope to build in Flushing Meadow Park.?

MORE: MLS expansion updates from Commissioner Garber

When asked if the New York Cosmos were going to be the 20th team, Garber refused to answer instead?saying that he and MLS support what the NASL is doing.?Garber did claim, however, that he believes MLS will continue its expansion beyond 20 teams by the end of 2020. But 30 teams? That would be too much of a leap.??It?s hard to imagine we?d have 30 teams,? Garber said. ?The other major leagues are around that size, they?ve been around 100 years.?

The league and the City have previously?been engaged in negotiations to build a stadium on a ten acre site in the Queens-based park with the goal of having a team begin playing there by 2016. On Thursday, Garber spoke again on the issue with the Associated Press, informing reporters that there are no other possible sites for a new stadium. ?If we get this done, it will be in Flushing Meadow Park. There is no Plan B.?

While New York is the league?s preferred choice for expansion, Orlando, Miami and Atlanta have all been linked as possible MLS expansions while USL Pro side Orlando City recently secured a $8.2m downtown parcel of land where they plan to build a new soccer-specific stadium.

Source: http://prosoccertalk.nbcsports.com/2013/04/25/mls-set-to-announce-plans-for-20th-team-in-new-york-city/related/

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NBA's Michael Jordan marries ex-model over weekend

Michael Jordan got married over the weekend, with Tiger Woods, Spike Lee and Patrick Ewing among those attending the NBA Hall of Famer's wedding in Palm Beach, Fla.

Jordan married 35-year-old former model Yvette Prieto on Saturday, manager Estee Portnoy told The Associated Press on Sunday.

The 50-year-old Jordan owns the Charlotte Bobcats.

Nearly 300 guests were present as they exchanged vows. The reception took place at a private golf club in Jupiter designed by Jack Nicklaus. Jordan owns a home near the course.

Entertainment included DJ MC Lyte, singers K'Jon, Robin Thicke and Grammy Award winner Usher and The Source, an 18-piece band.

The six-time NBA champion and Prieto met five years ago and were engaged last December.

Jordan had three children with former wife Juanita Vanoy. The couple's divorce was finalized in December 2006.

Source: http://news.yahoo.com/nbas-michael-jordan-marries-ex-model-over-weekend-024122152.html

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Amanda Knox opens up about experiences in Italian prison



>>> now to the trial that captivated italy and the book being released. amanda knox "waiting to be heard" she found out next month she will be retried.

>>> joining my nina burly, whose own book chronicled her time. nina , nice to see you. she reveals during her time in prison that doctors lied that she was hiv-positive. she thought about suicide. she fought off advances by a guard. how important to you think it was for her to write this book and get this published?

>> well, it was important for her to get out of jail. i think that was the first thing. the second is what kind of information is in that book, what is it that we're going to learn. from all the accounts that i have read, you know, prison is pretty boring, it's a pretty boring place. so unless she had kind of revealed something about what happened that night that we didn't already know about, or something about the case itself that we didn't already know about, i think we were, you know, we're going to be kind of underwhelm underwhelmed. was it important to write the book? well, you know, for her to have gone through four years in prison without being ability to get compensated for it through the italian system, the fact that harper collins gave her $4 million to write it, reportedly, is some sense of compensation for the time spent in prison.

>> but we have to also remember that a young woman lost her life that day in italy of knox says he wants them to read the book. are they going to get something if they read the book?

>> they're not going to get anything from reading the book, as far as i can tell. that family is very convinced that amanda knox killed their daughter. so they're not going to be reading the book. i think they're very upset about the fact that she got that much money, and one of the reasons why they're not publishing the book in the uk is that there are apparently lots of libel laws, it's easier to file a libel suit there, so they're not going to be satisfied by it.

>> real quick, nina , were you surprised when the high court in italy ordered a retrial?

>> yes, i was, absolutely. i was surprised. there isn't a lot of evidence that these two young people were involved in the case, but then again, the italian system has to work its way through. it's different from ours. it's legitimate for them. the prosecutor can bring an appeal.

Source: http://feeds.nbcnews.com/c/35002/f/653381/s/2b46919e/l/0Lvideo0Bmsnbc0Bmsn0N0Cid0C51694343/story01.htm

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Sunday, April 28, 2013

Rehtaeh Parsons' parents speak out against Postmedia chain's ...

Yesterday, April 26, Postmedia writer Christie Blatchford published a column across the media chain hitting back at the campaign against sexual violence in Nova Scotia that has been sparked by the recent suicide of 17-year-old Rehtaeh Parsons. The young woman's father, Glen Canning, has published a statement replying to the columnist. The text of his statement is below.

Leah Parsons, Rehtaeh?s mother, has also responded to the column, on a Facebook page, 'Angel Rehtaeh,' dedicated to her daughter. Her response to the columnist reads, in part, ?This article clearly highlights the ?slut shaming? going on in our country and the abuse that Rehtaeh felt over and over for the past 18 months. If a grown woman can write such a biased, degrading, harassing article, think of how a 15 yr old was able to deal with the torment of those young boys. I only pray that you do not have any daughters or granddaughters.?

Postmedia's outlets are publishing articles today that report on Glen Canning's statement. The National Post version also includes information on Leah Parsons' response.

I wrote a letter today to the National Post and Vancouver Sun, text below. In it, I highlight issues of failed, institutional reaction to the original assault against Rehtaeh Parsons in 2011. I wrote about this in my original article on the subject.?

Halifax writer and an editor of The Coast weekly, Tim Bousquet, has just penned a lengthy, informed commentary on Rehtaeh Parsons' case entitled, 'The shame of slut-shaming.' The large number of comments accompanying his article are indicative of the intensity of the public debate taking place in Nova Scotia over the need to combat sexual violence. This is a positive outcome to an otherwise tragic series of events.

Addressing Christie Blatchford?s article

By Glen Canning, published on Scrib.com, April 26, 2013

This morning I woke up and read an article in the National Post about Rehtaeh?s case. I?m not upset or mad. A little disappointed maybe. The writer, Christie Blatchford, makes a few statements I would like to address.

?What they had was a complainant whose evidence was all over the map, independent evidence that supported the notion that any sex was consensual, and no evidence that Rehtaeh was so drunk that she couldn?t consent: The case was a mess.? ~ Christie Blatchford

?What they had was a complainant whose evidence was all over the map??

Rehtaeh was intoxicated at the time and she has always stated she couldn?t remember much of what happened. What she did say was all over the map and that is exactly what one should expect it to be from a 15 year old girl who remembers very little but is being swamped at school and online with slut stories about what took place.

??independent evidence that supported the notion that any sex was consensual, and no evidence that Rehtaeh was so drunk that she couldn?t consent.?

The two boys involved in taking and posing for the photograph stated Rehtaeh was throwing up when they had sex with her. That is not called consensual sex. That is called rape. They also stated they had to get her dressed when they were finished. She was passed out. That is the story they told to anyone at Rehtaeh?s school who would listen. That is their account of what happened. There are numerous people who heard that and shared that. No evidence she was so drunk that she couldn?t consent? How drunk does someone have to be? Drunk enough to get sick or drunk enough to not remember?

The photo is of a male naked from the waist down, giving a thumbs-up sign, pressing into the bare behind of another person who is leaning out a window. What the picture doesn?t reveal, however, is a recognizable face, if there even was a sexual assault going on, or if the second person was a female.?

What did the person in the photograph say? That it was him, that the female was Rehtaeh, that she was vomiting, and that he was having sex with her. He repeated that story many times to many people all while texting that photo to God knows who. Hard to believe that could be presented to the Crown and dismissed but there you go.

?But there are two sides, even to this wrenching tale.?

With that I agree. There are two sides. Rehtaeh?s side, that she was intoxicated, throwing up, and raped; and the boys' side, that she was intoxicated, throwing up, and she wanted to have sex. So in the end all we?re left with is the Criminal Code of Canada that states pretty clearly that what happened to Rehtaeh Parsons is called rape. Even if there was consensual sex before Rehtaeh passed out and got sick once she was in that state consent is no longer there. That?s not called regret, it?s called the law.

So why weren?t they charged? I honestly have no idea. Reading the statistics it?s not surprising but I have no idea in this case. The boys who raped Rehtaeh bragged about it. They photographed it. There?s more evidence in Rehtaeh?s case then there was in the Steubenville case.

?Proving the modern maxim that she who gets to social media first may set the script in stone, the post ignited a firestorm.?

That is exactly what happened to Rehtaeh. The slut story spread around her school like a firestorm via social media while she desperately tried to deal with it. Her efforts weren?t perfect but she did her best. Sorry it wasn?t the 100% perfect case that rape victims need in this country in order to get justice but she tried. And for that I am very proud of her.

I told Rehtaeh all the time that justice is a long shot and even than people will think she either asked for it, or she deserved it. I just wanted her to be prepared. She just wanted to be believed.

She mentioned last year a friend of hers was raped under similar circumstances by one of the same boys. I jumped at that because it would help support her case but Rehtaeh?s friend wasn?t interested in coming forward or talking to the police. She said she watched what had happened to our daughter and there was no way she was going to put herself through that. Who can blame her? Isn?t that why most rape victims say nothing? Because it?s never about the rapist, it?s always about the victim.

?The girlfriend of Rehtaeh?s who was at the party told police Rehtaeh was being flirtatious, ??

It?s always about the victim.

Letter to the Vancouver Sun

Vancouver BC
April 26, 2013

Christie Blatchford?s claim that an inebriated 15-year old Rehtaeh Parsons could have engaged in consensual sex on the night of the assault she suffered in 2011 is outrageous.

There are so many important parts of this story that Blatchford ignores. The disappointing, to say the least, conduct of education officials throughout the Parsons case. Why the alleged assailants would circle their wagons so firmly and then lash out, if the assault in question never occurred. And the law and order hue and cry of the prime minister of Canada and Nova Scotia government that effectively backs the 2012 decision of police and judicial investigators to not lay charges and perpetuates a myth that existing law is inadequate to protect the victims of sexual assault.

The writer is very concerned that the case of Rehtaeh Parsons has been falsely presented. But she appears entirely unconcerned about the broader societal issues of sexual assault, including the urgency of changes in our governing and judicial institutions such that victims or potential victims are better protected.

Roger Annis

Source: http://rabble.ca/blogs/bloggers/roger-annis/2013/04/rehtaeh-parsons-parents-speak-out-against-postmedia-chains-shamef

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Meet Some Hackers And Their Promising Projects At The Disrupt NY Hackathon

hackcrowd13It's only been about six hours since our Disrupt NY Hackathon officially began, and we're starting to see our intrepid hackers hit their stride. Granted, some of them are a little farther along than others -- Darrell found one guy who made an Arduino-powered robot for physically testing apps and devices -- but there's still plenty of time to bring some of these wild-eyed designs to fruition. Let's take a peek at what everyone else is working on, shall we?

Source: http://feedproxy.google.com/~r/Techcrunch/~3/TRN2PbCd_qU/

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Fiery Afghan bus crash kills 45, Taliban blamed

KANDAHAR, Afghanistan (AP) ? A bus collided on Friday with the wreckage of a truck that had been attacked by Taliban insurgents in southern Afghanistan, killing 45 people aboard the bus in a fiery crash, officials said.

The battered oil tanker had been left in the middle of a narrow road near the border of Kandahar and Helmand provinces for several days after insurgents attacked it. Police considered the area too dangerous to enter, the officials said.

Before sunrise Friday, the bus smashed into the truck and burst into flames, said Abdul Razaq, the provincial police chief of Kandahar.

As police, soldiers and ambulances rushed to the desolate area, where many of the victims were burned beyond recognition, one survivor, Mohammad Habib, cried as he searched for his brother.

"I don't care about my belongings and money that were burned inside the bus, but please help me find my brother, dead or alive," he told AP Television News. "How will I face my mother without him?"

Forty-five people were killed and 10 injured, said Javeed Faisal, the spokesman for the governor of Kandahar province. He spoke to The Associated Press at Mirwais Hospital in Kandahar city, where many of the victims, including men, women and children, were being taken.

Razaq said it would be difficult to identify many of the bodies.

The bus began its journey in the capital of Helmand province and was to stop in Kandahar city, then travel north to Kabul, the Afghan capital, Razaq said.

Meanwhile, Afghan and coalition forces continued to conduct joint operations around Afghanistan.

They arrested about 10 insurgents on Thursday and Friday in four provinces of Afghanistan, including several Taliban fighters in Kandahar, the International Security Assistance Force said in a statement.

---

AP writers Thomas Wagner and Amir Shah in Kabul contributed.

Source: http://news.yahoo.com/fiery-afghan-bus-crash-kills-45-taliban-blamed-121520376.html

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Figuring Out Fatherhood: How fortunate we are - Parentdish UK

Figuring Out Fatherhood: How fortunate we areAlamy

I often complain about being a parent. It's the late nights and early mornings; the lack of free time to just wander down to the pub on a whim when it's a lovely spring evening; the way I have to mentally prepare myself for a few minutes before logging onto my online bank account and seeing just how much money I haven't got.

It's not just me, though: complaining about being a parent is something shared between every mother and father. Those who say that they never complain are - for want of a better word - liars.

Don't get me wrong: being a parent is rewarding, often wonderful - but always exhausting. And did I mention that bringing up a child costs a lot?!

But it's easy to forget just how privileged I am to be a father.

Recently, two very good friends of ours lost a baby shortly after he was born prematurely.

Their grief is unlike anything I've ever seen before. Their days, which were once spent decorating a nursery or browsing the shelves of maternity stores, are now spent mourning the loss of their baby in a house which is silent.

Not only are they mourning their baby, but they are mourning everything their baby could have been and could have done: his first steps, his first day at school, graduation from university...the day he gives them a grandchild.

The funeral service was heartbreaking, the coffin so small. As the grief-stricken parents clutched each other at their son's graveside you could clearly see that they would have given anything to be woken by his cries in the night, to experience the difficulties of potty training, to have no spare time or no money, because it would mean they had a child they could hold, instead of one who they had to say goodbye to.

i

I can be almost certain that I was not the only parent who held their child a little closer - and for a little longer - on the evening of the funeral. It is so easy to see the negatives of parenting that I think sometimes we miss the glaring positive: that we are parents in the first place.

i

Ultimately, I hope that in realising this I can become a better father, that next time I will bite my tongue if my sons are being rowdy, or not consider it such a terrible thing if my eight-month-old daughter is sick all down her new dress; because it is likely that somewhere, not far away, is a person who would give anything to be as fortunate as I am.

Source: http://www.parentdish.co.uk/baby/how-fortunate-we-are-to-be-parents/

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Saturday, April 27, 2013

Researcher studies hormone levels and sexual motivation among young women

Friday, April 26, 2013

Feeling frisky? If so, chances are greater your estrogen level ?? and, perhaps, fertility ?? are hitting their monthly peak. If not, you're more likely experiencing a profusion of desire-deadening progesterone, and the less fertile time in your cycle. Oh, the power of hormones.

Researchers have long suspected a correlation between hormone levels and libido, but now scientists at UC Santa Barbara, led by James Roney, a professor in the Department of Psychological and Brain Sciences, have actually demonstrated hormonal predictors for sexual desire. Their findings appear in the current issue of the journal Hormones and Behavior.

"We found two hormonal signals that had opposite effects on sexual motivation," said Roney, the article's lead author. "Estrogen was having a positive effect, but with a two-day lag. Progesterone was having a persistent negative effect, both for current day, day before, and two days earlier." When hormone levels and sexual desire were factored against the menstrual cycles of test subjects ?? in this case, undergraduate students ?? the researchers saw a measurable increase in progesterone levels at the same time the subjects noted decreases in sexual motivation. Progesterone, the researchers say, is mediating this drop in desire from the fertile window to the luteal phase ?? the second half of the menstrual cycle.

"Progesterone acting as a potential stop signal within cycles is a novel finding in humans," noted Roney. "We know in rhesus monkeys there is a strong negative correlation with progesterone and a positive correlation with estrogen. The patterns are actually comparable to what you see in non-human primates, but hadn't been shown in humans."

The researchers' findings have potential implications on the treatment of low sexual desire and how hormone replacement trials are done. "We're not controlling hormones the way they do in the hormone replacement literature, so, in a sense, that literature is more directly applicable in terms of medical applications," said Roney. "But in the long run, it would be good to have a model of the combination of signals that operates in the natural cycle. The way hormone replacement trials are done now, there's no model of the natural signals, so they're sort of random ?? let's give estrogen, let's give testosterone, let's combine them this way or that way."

Roney noted that his findings don't present a full model, and he'd like to replicate his results with women of different age groups. "Undergraduates might be unique for a lot of reasons," he said. "Their hormone levels tend to be a bit different from those of women even just a little bit older. And married women in their 30's are likely to be more consistently sexually active, and that might change the patterns in some ways. They also tend to have higher hormone secretion and more regular cycles than younger women," he said

Eventually, Roney continued, the goal would be to have a better model of the signals in a natural cycle that might then inform medical research.

Another interesting finding, according to Roney, was the impact ?? or lack thereof ?? of testosterone on the women's sexual motivation. "There's a common belief in the medical literature that testosterone is the main regulator of women's libido," he explained. "Doctors tend to believe that, though the evidence isn't that strong in humans. In the natural cycles, we weren't finding effects of testosterone. It wasn't significantly predicting outcomes."

Roney doesn't deny that testosterone does seem to have a positive effect in hormone replacement therapy, but suggests the effects may be pharmacological. "Testosterone has those effects if you inject it externally in women who are menopausal, and there are a lot of reasons that might be the case," he said. "For example, testosterone can be converted to estrogen through a particular enzyme. If you inject menopausal women with testosterone, it might be acting as a device that's delivering estrogen to the target cells. So the fact that it works doesn't necessarily mean it's an important signal in the natural cycle."

###

University of California - Santa Barbara: http://www.ucsb.edu

Thanks to University of California - Santa Barbara for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/127964/Researcher_studies_hormone_levels_and_sexual_motivation_among_young_women

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This Week On The TechCrunch Gadgets Podcast: The Q10 Vs. The One And The Fitbit Flex

podcastThis week on the TechCrunch Gadgets Podcast we talk about the Blackberry Q10, The HTC One, and the Fitbit Flex. This time we're joined by Matt Burns, Darrell Etherington, Chris Velazco, and a tiny thinger that won't fit into the bracelet. Enjoy!

Source: http://feedproxy.google.com/~r/Techcrunch/~3/F7p02rYk-l0/

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New Smartphone Technology Keeps Work And Personal Lives ...

This post is sponsored by BlackBerry.

Maintaining a work-life balance means trying to keep?

More: New Smartphone Technology Keeps Work And Personal Lives Separate

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Young musicians cling to Cajun, zydeco traditions

NEW ORLEANS (AP) ? Members of the Cajun band T'Monde are young, but they like their music old.

The band of 20-somethings opened the New Orleans Jazz and Heritage Festival on Friday with century-old, fiddle-heavy Cajun tunes.

As music fans carried folding chairs and umbrellas through the gates of the Fair Grounds horse racing track, band leader and accordion player, Drew Simon (SEE-mon), sang in Cajun French.

T'Monde (TEE'-Mone) loosely translated means "little world" or "little people." The group opened one of the festival's 12 stages. Also on the lineup were Dr. John, blues guitarist Gary Clark Jr., John Mayer, George Benson and Terrance Simien.

Jazz Fest continues through Sunday and May 2-5.

Source: http://news.yahoo.com/young-musicians-cling-cajun-zydeco-traditions-163606589.html

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"Chief Porn Identification Officer:" The Best Job You'll Never Have

If you could do anything—anything—for a living what would it be? Well that's dumb; it would be "looking at porn." And though you may not be so lucky, someone working for China will be, boasting the prestigious title of Chief Porn Identification Officer. More »
    


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/5FrLPOBZtqE/chief-porn-identification-officer-the-best-job-youll-never-have

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Friday, April 26, 2013

Israeli military shoots down drone

(AP) ? Israel shot down a drone Thursday as it approached the country's northern coast, the military said. Suspicion immediately fell on the Hezbollah militant group in Lebanon.

The incident was likely to raise already heightened tensions between Israel and Hezbollah, a bitter enemy that battled Israel to a stalemate during a monthlong war in 2006.

Prime Minister Benjamin Netanyahu, who was in northern Israel at the time of the incident, said he viewed the infiltration attempt with "utmost gravity."

"We will continue to do everything necessary in order to protect the security of the citizens of Israel," he said.

Lt. Col. Peter Lerner, a military spokesman, said the unmanned aircraft was detected as it was flying over Lebanon and tracked as it approached Israeli airspace.

Lerner said the military waited for the aircraft to enter Israeli airspace, confirmed it was "enemy," and an F-16 warplane shot it down.

The drone was flying at an altitude of about 6,000 feet (1,800 meters) and was downed roughly five miles (eight kilometers) off the Israeli coast near the northern city of Haifa. Lerner said Israeli naval forces were searching for the remains of the aircraft.

He declined to say who sent the drone. But other military officials, speaking on condition of anonymity because they were not permitted to talk to the media, said they believed it was an Iranian-manufactured aircraft sent by Hezbollah. Hezbollah sent a drone into Israeli airspace last October that Israel also shot down.

Netanyahu was informed of the unfolding incident as he was flying north for a cultural event with members of the country's Druse minority. Officials said his helicopter briefly landed while the drone was intercepted before Netanyahu continued on his way.

Netanyahu repeatedly has warned that Hezbollah might try to take advantage of the instability in neighboring Syria, a key Hezbollah ally, to obtain what he calls game-changing weapons.

Israel has all but confirmed that it carried out an airstrike in Syria early this year that destroyed a shipment of sophisticated anti-aircraft missiles bound for Hezbollah.

A senior Lebanese security official, who also spoke on condition of anonymity in line with regulations, said Lebanon had no information on Thursday's incident.

Hezbollah spokesman Ibrahim Moussawi also said he had no information, adding the group would put out a statement if it had something to say on the issue.

When Israeli military shot down a Hezbollah drone on Oct. 6, it took days for Hezbollah leader Sheik Hassan Nasrallah to confirm it in a speech. He warned at the time that it would not be the last such operation by the group. He said the sophisticated aircraft was made in Iran and assembled by Hezbollah.

___

Associated Press writers Zeina Karam in Beirut and Diaa Hadid in Jerusalem contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2013-04-25-ML-Israel-Hezbollah/id-f26c8317f5be4c90a7f7c1bdc119ab3c

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Acer Aspire V5-571PG-9814


We've seen a lot of systems come through the PC Labs with touch screens?tablets, convertible PCs, all-in-one desktops, and touch-friendly ultrabooks?but for a lot of these systems, touch was the crowning feature, the shiny bit of flash to draw a buyer's attention. The Acer Aspire V5-571PG-9814 does things a little differently. While it does have a touch screen, the overall design is a little bland, and the design, while fairly trim, isn't supermodel thin. What should catch your attention, however, is the hardware hidden inside?a newer, faster Intel Core i7 and a discrete Nvidia GPU. The combination of speedy hardware and solid (if not flashy) design should have more than a few shoppers considering the Aspire V5-571PG over competitors like the Editors' Choice Asus VivoBook S400CA-UH51 ($699 direct, 4 stars) or the HP Spectre XT TouchSmart 15-4010nr.

Design and Features
The Aspire V5-571PG has a slim chassis and falls into that nebulous area between slim ultrabooks, thick ultrabooks with touch, and standard notebooks. While it is slim?1.0 by 13.5 by 9.6 inches (HWD)?and touch-enabled, it's no ultrabook, lacking the required solid-state drive or flash cache needed for the much touted snappy performance that Intel demands. That said, it's a fairly slim laptop, and given that it offers a capacitive touch screen with 10-digit tracking, it looks surprisingly svelte. It's also light for a 15-inch system, at 4.63 pounds.

The 15.6-inch display offers 1,366-by-768 resolution, in addition to the touch capabilities, with decent viewing angles and Acer's Active Matrix TFT Color LCD. Joining the display is Dolby Advanced Audio v2 enhancement software, producing sound that, while not spectacular, offers good volume. The sound is a bit reedy, and offers almost no bass, but it will do for regular use. The chiclet keyboard offers both a full-size keyboard and a compact numeric pad?the number keys are narrow, but still very usable?with backlight for better low-light visibility. The touchpad is comfortably large, with right- and left-buttons integrated into the clickpad surface.

You'll find the usual collection of ports on the sides of the laptop, but one may be unfamiliar?Acer's proprietary combination Ethernet and VGA, which we've seen before on the Acer Aspire V5-571-6869The slim port saves space and eliminates a second port, but requires a special (included) adapter dongle, which you'll need to remember to bring along if you want to use either connection.

The Aspire V5-571PG offers three USB ports (one 3.0 and two 2.0), HDMI output for connecting to a projector or HDTV, and a multiformat card slot. A tray-loading DVD+-RW dual-layer drive takes care of your disc-burning needs, while 802.11n Wi-Fi gets you online without hassling with the included Ethernet adapter. Inside the laptop is a generous 1TB hard drive, which should offer enough storage space for a healthy digital life, full of photos and media files.

Acer doesn't hold back on the preinstalled software, starting with several proprietary programs, like Clear.fi Photo and Media, for locally sharing media va Wi-Fi, and Acer Cloud, which lets you backup and access your files anywhere there's a web connection. But the programs don't stop there, with plenty of extras piling on?Amazon Kindle, ChaCha, eBay, Encyclopedia Britannica, Evernote, Hulu Plus, iCookbook, Netflix, newsXpresso, Skitch, Skype, SocialJogger, Spotify, StumbleUpon, TuneIn Web radio, and a handful of sample games from Wild Tangent. You'll need a good 30 minutes to clear off all the unwanted crud, but a number of those utilities may be useful enough to keep. Additionally, Acer covers the Aspire V5-571 with a one-year hardware warranty, and 90-days of free software support.

Performance
Acer Aspire V5-571PG-9814 The V5-571PG-9814 is outfitted with a 2GHz Intel Core i7-3537U dual-core processor, a step up from the ultra-mobile Core i7 seen in the HP Spectre XT Touchsmart 15-4010nr. Paired with 8GB of RAM, it offered better overall performance than comparable systems, racking up 2.84 points in Cinebench, well ahead of the leading Asus VivoBook S400CA-UH51 (2.40 points), and topping the HP Spectre XT (1.97 points). The faster processor led to better performance, as seen in Handbrake, where the Acer Aspire led in both Handbrake (1 minute 13 seconds) and Photoshop (4 minutes 22 seconds).

Acer Aspire V5-571PG-9814

But where the V5-571PG-9814 really takes the cake is graphics performance, thanks to a discrete Nvidia GeForce 710M graphics processor. It pounded through 3DMark 11 with leading scores?1,981 points at Entry settings and 358 at Extreme settings?and then beat out all competitors in our gaming tests. The discrete GPU won't be enough to let you play high-end games like Skyrim or Crysis 3, but for less demanding titles, like Team Fortress 2 or League of Legends, you'll be able to get in on the game.

Last but not least, the 4-cell lithium ion battery sealed into the V5-571PG-9814 lasted 3 hours 37 minutes in our rundown test?a 12-hour loop of the entire Extended Edition Lord of the Rings Trilogy?which isn't terrible, but it does come up short when compared with competitors, like the Asus VivoBook S400CA-UH51 or the Sony VAIO T15 Touch (SVT15112CXS), which both lasted 4:18 (give or take a few seconds).

While it fell short in battery life and doesn't impress with its bland looks and middling port selection, the Acer Aspire V5-571PG-9814 does offer the best all-around processing and graphics performance of any of the 14- and 15-inch touch-screen laptops we've seen in recent months. While raw performance isn't enough to take the Editors' Choice from the Asus VivoBook S400CA-UH51, it is enough to recommend it to anyone shopping for a reasonably priced touch-enabled Windows 8 laptop.

Source: http://feedproxy.google.com/~r/ziffdavis/pcmag/~3/98ZNUKs7Kbc/0,2817,2418122,00.asp

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CA-BUSINESS Summary

TSX clocks sixth day of gains on U.S. data, Potash results

TORONTO (Reuters) - Canada's main stock index advanced for a sixth straight session on Thursday, helped by resources sectors as U.S. economic data and a stronger-than-expected earnings performance from fertilizer producer Potash Corp buoyed sentiment. Investors were encouraged by data showing the number of Americans filing new claims for unemployment benefits fell last week, offering reassurance that the bottom is not falling out of the U.S. labor market.

Yahoo Chairman Fred Amoroso resigns

(Reuters) - Yahoo Inc Chairman Fred Amoroso is resigning effective immediately, the struggling Internet company announced on Thursday. Amoroso will be replaced in the chairman role by director Maynard Webb Jr. on an interim basis until the company's annual shareholder meeting on June 25.

Amazon growth slows, while profit margins expand

SAN FRANCISCO (Reuters) - Amazon.com Inc's revenue growth slowed in the first quarter as the world's largest Internet retail struggled overseas, but margins jumped on lower shipping expenses and the expansion of more profitable new businesses. Amazon shares fell 1.9 percent to $269.43 in after-hours trading on Thursday following the results.

Starbucks raises outlook but shares fall

(Reuters) - Starbucks Corp reported higher quarterly profit on Thursday that matched Wall Street estimates and it raised its full-year earnings forecast. The world's biggest coffee chain cited increased sales in the United States, its top market, despite an industry-wide spending downturn in February due to a U.S. payroll tax increase that lowered take-home pay.

BOJ stands pat, to face credibility test with new forecasts

TOKYO (Reuters) - The Bank of Japan will probably project on Friday that it will meet its 2 percent inflation target in two years due to its massive stimulus plan, a forecast analysts say may be too optimistic and which could put its credibility on the line. In a reminder of how ambitious and stiff the target is, data on Friday showed core consumer prices marked their fifth straight month of annual declines in March even as the yen's recent falls pushed up import costs.

Samsung Electronics profit jumps ahead of Galaxy S4 debut

SEOUL (Reuters) - Samsung Electronics Co Ltd reported on Friday its sixth straight quarter of profit growth ahead of the debut of its latest Galaxy smartphone, the South Korean IT giant's biggest assault on rival Apple Inc yet. By launching the Galaxy S4 in the United States on Saturday, Samsung is taking aim at Apple's home market at a time when the iPhone maker appears to have hit a snag. Earlier this week, Apple reported its first profit decline in more than a decade and indicated no major product releases until the fall.

Monte Paschi committed to avoid state becoming majority shareholder: CEO

MILAN (Reuters) - Italy's Banca Monte dei Paschi di Siena is committed to avoiding the state becoming a majority shareholder in the bank, chief executive Fabrizio Viola said on Friday. "One thing is having the state as minority shareholder another is imagining the majority becomes public: this latter is a scenario certainly possible but the bank is committed to avoid it," Fabrizio Viola said in an interview in Il Sole 24 Ore.

Asian shares rise on U.S. data, regional earnings eyed

TOKYO (Reuters) - Asian shares rose on Friday, tracking global equities higher after upbeat U.S. labor market data, while the dollar eased slightly on currency markets that were otherwise watching for the strength of signals coming from a Bank of Japan policy review. In the share markets, investors turned attention toward regional corporate earnings to assess the outlook for growth.

New York drops damages claim in suit against ex-AIG chief

NEW YORK (Reuters) - New York's attorney general is dropping a claim for damages in a high-profile civil lawsuit accusing the former chief executive of American International Group Inc , Maurice "Hank" Greenberg, of defrauding investors, according to a letter sent by the attorney general's office on Thursday. The 2005 lawsuit filed by then-Attorney General Eliot Spitzer against Greenberg and former AIG chief financial officer Howard Smith sought as much as $6 billion in damages.

U.S. seizes on ruling to boost Wells Fargo mortgage fraud case

NEW YORK (Reuters) - The Justice Department has promptly capitalized on a court victory to bolster a case before another federal judge, citing a ruling on Wednesday that endorsed the agency's use of a little known financial fraud law to prosecute bank actions during the financial crisis. In a letter made public on Thursday, the agency told District Judge Jesse Furman on Wednesday that the ruling is one reason why its mortgage-fraud case against Wells Fargo & Co should not be dismissed.

Source: http://news.yahoo.com/ca-business-summary-004019720--finance.html

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Thursday, April 25, 2013

"Slacker" Kudrin turned down job offer: Russia's Putin

By Douglas Busvine

MOSCOW (Reuters) - Russian President Vladimir Putin jokingly called former Finance Minister Alexei Kudrin a "slacker" on Thursday for refusing to rejoin his government, as the two jousted on live television over how to revive a weakening economy.

"I offered - he refused," Putin told a live call-in show after Kudrin took the microphone to criticize his administration's economic policies. Smiling, Putin added: "He's a slacker and doesn't want to work."

The good-natured exchange indicated that, although Putin remains on good personal terms with Kudrin, who served as finance minister for 11 years before resigning in September 2011, their economic views remain far apart.

Since quitting, Kudrin has publicly sympathized with opposition protests over alleged ballot fraud in the ensuing parliamentary and presidential elections that secured Putin's return for a third Kremlin term.

His presence in the audience of Putin's annual question-and-answer session and his tough questions were probably stage-managed to show that Putin could tolerate hard questioning.

Kudrin, a fiscal hawk and economic liberal, told Putin it was important to find political consensus and take into account the concerns of people who want to invest money and create jobs.

"As of today, we do not have a program to wean the economy off its dependence on oil," Kudrin said, adding that Russia's economic slowdown could be put down largely to domestic factors rather than weak export demand.

He said growth in Russia's $2 trillion economy slowed to 1.1 percent in the first quarter of this year - its weakest since of 2009 - even as government spending grew and pay rises outpaced growth in labor productivity.

Putin answered Kudrin's remarks by saying his government's primary task was to ensure the prosperity of the Russian people and that pay and pensions increases had been justified.

Kudrin "was the best finance minister - but would not be the best minister for social affairs", Putin said.

In separate comments, Putin said that the government's economic policies were fundamentally on the right track. He said what critics describe as excessively strict monetary policy was "justified", and supported a fiscal rule introduced last year that caps government borrowing based on a historical oil price.

Sources have said that Putin offered the position of central bank governor to Kudrin, but was refused. Putin eventually chose his most senior economic adviser, Elvira Nabiullina, to take the helm of the central bank in June.

(editing by Elizabeth Piper)

Source: http://news.yahoo.com/slacker-kudrin-turned-down-job-offer-russias-putin-095329001--business.html

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Chevy Spark EV rated 'most efficient' retail car with 82-mile range, 119 MPGe

Chevy Spark EV rated 'most efficient' retail car by EPA with 82-mile range, 119 MPGe

All EVs have their own particular merits: some climb, some race, some only have three wheels, and some are even prone to melting. Chevrolet's Spark EV may not have any of these credentials, but now it's found the right feather to fit its cap as the "most efficient" retail car. The US Environmental Protection Agency (EPA) estimates that the Spark has a combined city / highway range of 82 miles on a full charge of its 21 kWh battery, and has given the vehicle a rating of 119 MPGe (a gasoline-equivalent figure). As Autoblog notes, Honda's Fit EV will go 82 miles on a smaller 20 kWh battery but, once the regulators have done fiddling with digits, it only scores 118 MPGe. That's the efficiency number that matters, and whether you're saving the world or just trying to save money, every mile counts. You'll be able to put that EPA rating to the test this summer when the Spark EV goes on sale in California and Oregon, but until then, check out the official certificate below the fold for more juicy details (read: efficiency stats).

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Via: Autoblog

Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/sx6NJTXzwHw/

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Apple Sells 37.4M iPhones And 19.5M iPads In Q2, Tablet Business Shows 65% YOY Growth

iphone5Apple has just released its Q2 2013 earnings report, announcing sales of 37.4 million iPhones in the quarter ending March. Apple also reported 19.5 million iPad units sold, which shows incredibly strong growth for Apple's tablet business. This is a slight decrease from last quarter, which included a holiday sales spike and being the first full quarter in which the iPhone 5 was available.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/71C7a6G8z1Q/

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Western Digital's revenue beats on higher hard disk drive shipments

(Reuters) - Hard disk drive maker Western Digital Corp posted better-than-expected third-quarter revenue, helped by higher demand from enterprise customers.

Net income for the company, which along with Seagate Technology Plc dominates the hard disk drive market, fell to $391 million, or $1.60 per share, from $483 million, or $1.96 per share, a year earlier.

Revenue rose 24 percent to $3.76 billion.

Analysts on average had expected earnings of $1.77 per share on revenue of $3.61 billion, according to Thomson Reuters I/B/E/S.

Hard disk drive shipment rose 36 percent to 60.2 million units.

(Reporting by Supantha Mukherjee in Bangalore; Editing by Maju Samuel)

Source: http://news.yahoo.com/western-digitals-revenue-beats-higher-hard-disk-drive-203437915--finance.html

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Reid pushes sequester replacement plan (Washington Bureau)

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